As the global COVID-19 vaccine rollout gets underway, humanitarian organizations such as International Medical Corps are using their expertise in community health to mount effective vaccination campaigns in the countries where they work. With our decades of experience managing outbreaks of infectious disease—from helping to eradicate wild polio in Africa, to supporting cholera vaccinations in Haiti, to treating malaria in Yemen—we’ve seen how challenging it can be to deliver critical healthcare in remote areas and demanding environments. Here’s a look at what goes into effective last-mile delivery of vaccines and how International Medical Corps is supporting worldwide immunization efforts with staff, training, supplies and education. The “last mile” is a phrase used to describe the last leg of any product’s journey to its destination. This final journey could be just a few miles long—from a local warehouse to your front door, for example—or it could extend thousands of miles across challenging terrain. The last mile looks different for every product; when it comes to medication, it can get especially complicated. Many medicines, including vaccines, must be kept at consistent cold temperatures, which is where the concept of “cold chain” comes in. Cold chain involves the requirement for refrigeration to be constantly maintained from product creation to disbursement. If this chain is broken, and the product’s temperature rises above or falls below what it needs to stay viable, then the product’s shelf life shortens. In the worst cases, the product becomes unusable. “The cold chain has to be uninterrupted from the day the vaccine is manufactured until it’s administered to a patient,” explains Nikola Usenovic, Head of Global Procurement at International Medical Corps. “Imagine an invisible rope running all the way from the factory through ports and airports to warehouses, and finally to the patient. That rope cannot be cut anywhere.” Fortunately, International Medical Corps has supported last-mile delivery of vaccines throughout our 37-year history. Our teams around the world are ready for this challenge.